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26 principal research scientist jobs found

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Vertex
Dec 11, 2025
Senior Principal Research Scientist, Biomarkers Lead (Immunology)
Vertex Boston, MA, USA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Dec 11, 2025
Molecular and Cell Biology Principal Research Scientist, Targeted Drug Delivery
Vertex San Diego, CA, USA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
AbbVie
Nov 20, 2025
Full time
Principal Research Scientist I, Peptide Engineer
AbbVie North Chicago, IL, USA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
AbbVie
Nov 20, 2025
Full time
Principal Research Scientist - Modeling and Simulation
AbbVie Irvine, CA, USA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
AbbVie
Nov 20, 2025
Full time
Principal Research Scientist I, Peptide Engineer
AbbVie North Chicago, IL, USA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
AbbVie
Nov 20, 2025
Full time
Principal Research Scientist - Modeling and Simulation
AbbVie Irvine, CA, USA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
AbbVie
Nov 20, 2025
Full time
Principal Research Scientist - Modeling and Simulation
AbbVie Irvine, CA, USA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
Allergan
Nov 20, 2025
Principal Research Scientist
Allergan Redwood City, CA, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist I/II, BioInformatics - Clinical Drug Discovery
Allergan Sunnyvale, CA, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist I/II, PKPD Modeling
Allergan San Francisco, CA, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist II
Allergan Lake County, IL, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist, Molecular Core - Antibody Discovery
Allergan Worcester, MA, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist, Solid State Chemistry
Allergan Lake County, IL, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist, Translational Oncology - Clinical BioMarkers
Allergan Lake County, IL, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
Allergan
Nov 20, 2025
Principal Research Scientist, Translational/BioMarker Research Lead
Allergan Lake County, IL, USA
Allergan is now part of AbbVie. As one company, we have brought together over 30 brands and leadership positions, expanding and diversifying our product portfolio. Join us in making a remarkable impact on people’s lives around the world. As two great companies combine forces, we’ve centralized the job search experience to help us find world-class talent interested in working every day to discover and address many of the world’s most pressing health challenges. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.
UCB Pharma
Dec 11, 2025
Full time
Senior or Principal Data Scientist - Research Analytics
UCB Pharma Cambridge, MA, USA
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
Roche
Dec 09, 2025
Full time
Principal II Scientist, Applied Chemistry, Fluidic Systems, Research & Early Development
Roche Santa Clara, CA, USA
Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world’s largest biotechnology company and the global leader in in-vitro diagnostics.
Pfizer
Dec 08, 2025
Full time
Principal Scientist, Pharmaceutical Research & Development
Pfizer Bothell, WA, USA
A role at Pfizer is unlike any other. Offering talented individuals the opportunity to own a career with real impact, our people go to work each day in the knowledge that every development signifies real, positive progress. We all believe in our ability to improve the future of healthcare, and in our potential to transform millions of lives. Because in every part of the world, the work we do is reaching everyone, everywhere for almost every medical need. That means not just attracting the best and brightest talent. But also ensuring our colleagues can thrive in an environment and culture where we champion Diversity and Inclusion every day, around the world.
Merck
Dec 04, 2025
Full time
Associate Principal Scientist, Clinical Research (Animal Health)
Merck Rahway, NJ, USA
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
GlaxoSmithKline
Dec 01, 2025
Full time
Principal Scientist, Biologic AI Research and Design
GlaxoSmithKline Collegeville, PA, USA
We are a focused biopharma company. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and advanced technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/immunology and oncology).
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