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5 principal scientist jobs found in Boston

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Full time  (4)
Merck
Mar 09, 2026
Full time
Senior Principal Scientist, Translational Medicine, Immunology
Merck Boston, MA, USA
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Vertex
Mar 18, 2026
Senior Principal Research Scientist, Biomarkers Lead (Immunology)
Vertex Boston, MA, USA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Genentech
Mar 16, 2026
Full time
Senior Principal DSX Data Scientist
Genentech Boston, MA, USA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Mar 16, 2026
Full time
Senior Principal DSX Data Scientist
Genentech Boston, MA, USA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
AstraZeneca
Mar 12, 2026
Full time
Associate Principal AI Research Scientist (Fundamental AI Research for Digital Biology)
AstraZeneca Boston, MA, USA
At AstraZeneca our mission is to create an inclusive and equitable environment, where people feel they belong. Our ongoing commitment to inclusion and diversity means we’re future proofing our business. It allows us to push the boundaries of science and deliver life-changing medicines to more and more patients around the world.
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