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26 principal scientist jobs found in South San Francisco

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Science South San Francisco principal scientist
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Full time  (26)
Lilly Pharmaceuticals
Aug 21, 2026
Full time
Sr Scientist/Principal Scientist, Discovery Oncology (in vivo Biology)
Lilly Pharmaceuticals South San Francisco, CA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. 
Genentech
Aug 18, 2026
Full time
Principal Scientist, SOP & Workflow Automation Champion, AI for Drug Discovery (AIDD)
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD)
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal/Sr. Principal Scientist - Development
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist, Lab Head, Synthetic Immunity
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist, Peptide Therapeutics
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Senior Principal Scientist, Peptide Therapeutics
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Senior Principal Scientist -Bioanalytical Assay- Cell Therapy
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Senior/Principal Scientist, Computational Neuroscience, Computational Sciences Center of Excellence
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist (Computational Chemistry)
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist, Lab Head, Immunology, Cell Therapy
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Principal Scientist - Oligonucleotide Design and Chemistry
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Genentech
Aug 18, 2026
Full time
Senior Principal Scientist: Metabolomics/Cell Therapy Media Development
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
Amgen
Aug 11, 2026
Full time
Principal Scientist – PKDM (Large Molecule Project Team Representative)
Amgen Remote (South San Francisco, CA)
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do.
Amgen
Aug 11, 2026
Full time
Principal Scientist, Integrated Computational and Experimental Inflammation Discovery
Amgen South San Francisco, CA
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do.
Amgen
Aug 11, 2026
Full time
Principal Scientist - Medicinal Chemistry
Amgen South San Francisco, CA
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do.
Amgen
Aug 11, 2026
Full time
Principal Scientist, Inflammation
Amgen South San Francisco, CA
You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do.
AbbVie
Aug 10, 2026
Full time
Principal Scientist I, Biologics Analytical Research and Development
AbbVie South San Francisco, CA
We Create Medicines and Solutions That Make a Real Difference But it’s more than what we discover—it’s how we get there. WHO WE ARE Meeting the needs of our times AbbVie’s mission is to discover and deliver innovative medicines and solutions that address complex health issues and enhance people's lives.
Genentech
Aug 18, 2026
Full time
Senior Principal Machine Learning Scientist, AI Biology & Translation (AIBT)
Genentech South San Francisco, CA
Genentech, now a member of the Roche Group, is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. 
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