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47 senior principal scientist jobs found

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Pharmaceutical senior principal scientist
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Zoetis
Sep 03, 2026
Full time
Principal Scientist/Senior Principal Scientist, Process Chemistry
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Zoetis
Sep 03, 2026
Full time
Senior Principal Scientist - Global Biologics, Swine
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Vertex
Sep 03, 2026
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal Scientist, Agentic Systems Development for Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
UCB Pharma
Sep 03, 2026
Full time
Senior Principal Scientist - Translational Muscle Biology
UCB Pharma Cambridge, MA
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
Takeda Pharmaceutical Company Ltd
Sep 02, 2026
Full time
Senior/Principal Scientist, Analytical Cell Line Engineering and Bioassay Development
Takeda Pharmaceutical Company Ltd Lexington, MA
Takeda is a patient-focused, values-based, R&D-driven global biopharmaceutical company committed to bringing Better Health and a Brighter Future to people worldwide. 
Takeda Pharmaceutical Company Ltd
Sep 02, 2026
Full time
Senior/Principal Scientist Cell Based Potency Assay
Takeda Pharmaceutical Company Ltd Lexington, MA
Takeda is a patient-focused, values-based, R&D-driven global biopharmaceutical company committed to bringing Better Health and a Brighter Future to people worldwide. 
Sanofi
Sep 01, 2026
Full time
Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics
Sanofi Cambridge, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Novartis
Aug 26, 2026
Full time
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Novartis
Aug 26, 2026
Full time
Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Novartis
Aug 26, 2026
Full time
Senior Principal Scientist / Assoc Director, Oncology Translational Research
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Merck
Aug 26, 2026
Full time
Senior Principal Scientist, Veterinary Pathology Board Certified
Merck West Point, PA
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Merck
Aug 26, 2026
Full time
Senior Principal Scientist, Pharmacokinetics
Merck South San Francisco, CA
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Merck
Aug 26, 2026
Full time
Senior Principal Scientist, Clinical Research, Breast Cancer
Merck Rahway, NJ
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Merck
Aug 26, 2026
Full time
Senior Principal Scientist, Clinical Research, Thoracic Malignancies
Merck North Wales, PA
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Merck
Aug 26, 2026
Full time
Senior Principal Scientist, Clinical Research, Thoracic Malignancies
Merck Rahway, NJ
At Merck, known as MSD outside of the United States and Canada, we are unified around our purpose: We use the power of leading-edge science to save and improve lives around the world. 
Lilly Pharmaceuticals
Aug 21, 2026
Full time
Senior/Principal Scientist, Bioprocess Purification Development
Lilly Pharmaceuticals Indianapolis, IN
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. 
Lilly Pharmaceuticals
Aug 21, 2026
Full time
Senior Principal Scientist - Bioanalytical Research
Lilly Pharmaceuticals Louisville, CO
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. 
Lilly Pharmaceuticals
Aug 21, 2026
Full time
Senior/Principal Scientist – Peptide Technical Services & Manufacturing Science (TS/MS), API External Manufacturing
Lilly Pharmaceuticals Indianapolis, IN
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. 
Lilly Pharmaceuticals
Aug 21, 2026
Full time
Senior Principal Scientist, Analytical Sciences
Lilly Pharmaceuticals Watertown, MA
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. 
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