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23 senior principal jobs found

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Zoetis
Sep 03, 2026
Full time
Principal Scientist/Senior Principal Scientist, Process Chemistry
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Zoetis
Sep 03, 2026
Full time
Senior Principal Scientist - Global Biologics, Swine
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Vertex
Sep 03, 2026
Senior Principal AI Engineer
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal, Source to Pay Technology
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal Scientist, Agentic Systems Development for Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Medicinal Chemistry Senior Principal Research Scientist
Vertex San Diego, CA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
UCB Pharma
Sep 03, 2026
Full time
Senior Principal Programmer, Atlanta, GA
UCB Pharma Atlanta, GA
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
UCB Pharma
Sep 03, 2026
Full time
Senior Principal Programmer, Raleigh, NC
UCB Pharma Raleigh, NC
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
UCB Pharma
Sep 03, 2026
Full time
Senior Principal Scientist - Translational Muscle Biology
UCB Pharma Cambridge, MA
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
Thermo Fisher Scientific
Sep 03, 2026
Full time
Senior/Principal - Country Approval Specialist
Thermo Fisher Scientific Remote (NC)
At Thermo Fisher Scientific, we work together to accelerate research, solve complex analytical challenges, improve patient diagnostics, drive laboratory productivity and produce life-saving treatments for patients.
Sanofi
Sep 01, 2026
Full time
Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics
Sanofi Cambridge, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Novartis
Aug 26, 2026
Full time
Principal Scientist II/Senior Principal Scientist, PK Sciences Clinical Pharmacology Artificial Intelligence (AI) Lead (dual level posting)
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Novartis
Aug 26, 2026
Full time
Senior Principal Scientist / Assoc Director, Oncology Translational Research
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Novartis
Aug 26, 2026
Full time
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
Jazz Pharmaceuticals
Aug 20, 2026
Full time
Senior Principal Real World Analyst (RWA)-2
Jazz Pharmaceuticals Remote (Philadelphia, PA)
We have a strong patient-focused cul​​​​​​​ture at Jazz Pharmaceuticals that our employees believe in and pursue every day. It is clearly identified through our mission, vision and core values.
Jazz Pharmaceuticals
Aug 20, 2026
Full time
Senior Principal Statistician
Jazz Pharmaceuticals Remote (Palo Alto, CA)
We have a strong patient-focused cul​​​​​​​ture at Jazz Pharmaceuticals that our employees believe in and pursue every day. It is clearly identified through our mission, vision and core values.
Jazz Pharmaceuticals
Aug 20, 2026
Full time
Senior Principal Statistician
Jazz Pharmaceuticals Remote (Philadelphia, PA)
We have a strong patient-focused cul​​​​​​​ture at Jazz Pharmaceuticals that our employees believe in and pursue every day. It is clearly identified through our mission, vision and core values.
Bristol Myers
Aug 13, 2026
Full time
Senior Principal Scientist, Cancer Immunology, Discovery Biology, Oncology Thematic Research Center
Bristol Myers Seattle, WA
Bristol Myers Squibb is a global biopharmaceutical company committed to creating innovative medicines for millions of patients around the world fighting serious diseases in therapeutic areas such as oncology, hematology, immunology, cardiovascular and neuroscience. At the same time, we also nurture our own team with inspiring work and challenging career options.
Boehringer Ingelheim
Aug 13, 2026
Full time
Senior Principal/ Principal Scientist, Computational Safety
Boehringer Ingelheim Ridgefield, CT
For more than 125 years, Boehringer Ingelheim has been committed to the research and development of innovative medicines that help bring more health to patients and their families. As a privately-held, family-owned pharmaceutical company, Boehringer Ingelheim is able to take a long-term view and invest heavily in science.
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