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61 principal scientist jobs found

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Zoetis
Sep 03, 2026
Full time
Principal Scientist/Senior Principal Scientist, Process Chemistry
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Zoetis
Sep 03, 2026
Full time
PK/PD Principal Scientist
Zoetis Remote (United States)
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Zoetis
Sep 03, 2026
Full time
Senior Principal Scientist - Global Biologics, Swine
Zoetis Kalamazoo, MI
Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability.
Vertex
Sep 03, 2026
Analytical Development Principal Scientist
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal Scientist, Applied AI & Agentic Systems for Small-Molecule Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Senior Principal Scientist, Agentic Systems Development for Drug Discovery
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Principal Scientist, Separation Methods Expert, Analytical Science and Technology (AS&T), Vertex Pharmaceuticals (Boston)
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Aseptic Control Principal Scientist, MSAT
Vertex Boston, MA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
Vertex
Sep 03, 2026
Optics / Microscopy Principal Scientist
Vertex San Diego, CA
Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.
UCB Pharma
Sep 03, 2026
Full time
Senior Principal Scientist - Translational Muscle Biology
UCB Pharma Cambridge, MA
Working at UCB, you will discover a place where you can grow and express your full potential while living the life you want. You’ll do this in keeping with one simple question "how does my work create value for people living with severe diseases?"
Sanofi
Sep 01, 2026
Full time
Principal Scientist, Systems and Disease Biology
Sanofi Cambridge, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Sanofi
Sep 01, 2026
Full time
Principal Scientist - CMC Statistician
Sanofi Framingham, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Sanofi
Sep 01, 2026
Full time
Senior Principal Scientist/Principal Scientist, Real-World Evidence & Disease Genomics
Sanofi Cambridge, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Sanofi
Sep 01, 2026
Full time
Principal Scientist
Sanofi Waltham, MA
Sanofi is comprised of three core business units: Specialty Care, Vaccines and General Medicines. Consumer Healthcare will become a standalone business unit. Around the world, more than 100,000 people at Sanofi are dedicated to making a difference in patients' daily lives, wherever they live, and enabling them to enjoy a healthier life.
Regeneron
Sep 01, 2026
Principal Scientist, Formulation Development (DPDT)
Regeneron Tarrytown, NY
At Regeneron, we believe in the power of original thinking. Our company is built on breakthrough ideas; which is why we foster a spirit of openness, and strive to inspire from within. We are collaborative by design and driven by curiosity. Each one of us plays an active role in transforming people’s lives through our work. Regeneron’s people make us who we are, and we are truly more than a company – we’re a community. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the...
Regeneron
Sep 01, 2026
Principal Scientist, Precision Medicine Strategy Lead (Clinical Biomarkers)
Regeneron Tarrytown, NY
At Regeneron, we believe in the power of original thinking. Our company is built on breakthrough ideas; which is why we foster a spirit of openness, and strive to inspire from within. We are collaborative by design and driven by curiosity. Each one of us plays an active role in transforming people’s lives through our work. Regeneron’s people make us who we are, and we are truly more than a company – we’re a community. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the...
Regeneron
Sep 01, 2026
Principal Scientist
Regeneron NY
At Regeneron, we believe in the power of original thinking. Our company is built on breakthrough ideas; which is why we foster a spirit of openness, and strive to inspire from within. We are collaborative by design and driven by curiosity. Each one of us plays an active role in transforming people’s lives through our work. Regeneron’s people make us who we are, and we are truly more than a company – we’re a community. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the...
Regeneron
Sep 01, 2026
Principal Scientist, Hearing Loss and Vestibular Disorders
Regeneron Tarrytown, NY
At Regeneron, we believe in the power of original thinking. Our company is built on breakthrough ideas; which is why we foster a spirit of openness, and strive to inspire from within. We are collaborative by design and driven by curiosity. Each one of us plays an active role in transforming people’s lives through our work. Regeneron’s people make us who we are, and we are truly more than a company – we’re a community. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the...
Regeneron
Sep 01, 2026
Principal Scientist, Neuroscience / Genetic Medicine
Regeneron Tarrytown, NY
At Regeneron, we believe in the power of original thinking. Our company is built on breakthrough ideas; which is why we foster a spirit of openness, and strive to inspire from within. We are collaborative by design and driven by curiosity. Each one of us plays an active role in transforming people’s lives through our work. Regeneron’s people make us who we are, and we are truly more than a company – we’re a community. Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels! Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the...
Novartis
Aug 26, 2026
Full time
Principal Scientist II/Senior Principal Scientist, Modeling & Simulation (Dual Level Posting)
Novartis Cambridge, MA
At Novartis US, our mission is to reimagine medicine and discover new ways to improve and extend people's lives. As a leading global medicines company, we use innovative science and digital technologies to create transformative treatments in areas of great medical need. 
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